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The Kyowa Kirin Cares program can help you get the information and resources you need to start and stay with NOURIANZ.

Learn more about cost savings for NOURIANZ

Cost savings on NOURIANZ Eligible commercially insured patients may pay as little as $20 per month for each prescription of NOURIANZ. See full eligibility requirements, terms, and conditions at Kyowa Kirin Cares.

Filling your prescriptions for NOURIANZ:

  • NOURIANZ is available at CVS and Walgreens pharmacies
    Cost savings Filling your prescriptions
  • You can choose to pick it up at the pharmacy or have the prescription shipped to you
Learn more about available support services.

Frequently asked questions about NOURIANZ

  • What is an “off” episode or OFF time?
    • An “off” episode or OFF time is when a patient’s medications for Parkinson's disease (PD) are not working well, which can mean that motor symptoms, such as tremor and difficulty walking, are increased.

  • What is NOURIANZ?
    • NOURIANZ is a prescription medicine used with levodopa and carbidopa to treat adults with Parkinson's disease who are having “off” episodes.

  • Can NOURIANZ reduce OFF time?
    • In clinical trials, adult patients with Parkinson's disease (PD) who took NOURIANZ with levodopa, with or without other PD medications, had less OFF time. For these patients, OFF time was reduced by about 0.96 to 1.58 hours per day.

  • What are the possible side effects of NOURIANZ?
    • NOURIANZ may cause serious side effects, including:

      • uncontrolled sudden movements (dyskinesia). Uncontrolled sudden movements is one of the most common side effects. NOURIANZ may cause uncontrolled sudden movements or make such movements you already have worse or more frequent. Tell your healthcare provider if this happens
      • hallucinations and other symptoms of psychosis. NOURIANZ can cause abnormal thinking and behavior including:
        • being overly suspicious or feeling people want to harm you (paranoid ideation)
        • believing things that are not real (delusions)
        • seeing or hearing things that are not real (hallucinations)
        • confusion
        • increased activity or talking (mania)
        • disorientation
        • aggressive behavior
        • agitation
        • delirium (decreased awareness of things around you)

      If you have hallucinations or any other abnormal thinking or behavior, talk with your healthcare provider.

      • unusual urges (impulse control or compulsive behaviors). Some people taking NOURIANZ get urges to behave in a way unusual for them. Examples of this are unusual urges to gamble, increased sexual urges, strong urges to spend money, binge eating, and the inability to control these urges. If you notice or your family notices that you are developing any unusual behaviors, talk to your healthcare provider

      The most common side effects of NOURIANZ include uncontrolled movements (dyskinesia), dizziness, constipation, nausea, hallucinations, and problems sleeping (insomnia).

      These are not all the possible side effects of NOURIANZ.

      Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

  • What should my healthcare provider know before deciding if NOURIANZ may be right for me?
    • Before you take NOURIANZ, tell your healthcare provider about all your medical conditions, including if you:

      • Have a history of abnormal movement (dyskinesia)
      • Are pregnant or plan to become pregnant. NOURIANZ may harm your unborn baby
      • Are breastfeeding or plan to breastfeed. It is not known if NOURIANZ passes into breast milk. You and your healthcare provider should decide if you will take NOURIANZ or breastfeed
      • Have reduced liver function
      • Smoke cigarettes

      Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

      NOURIANZ and other medicines may affect each other causing side effects. NOURIANZ may affect the way other medicines work, and other medicines may affect how NOURIANZ works.

      Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

      • Talk to your doctor if you have any questions about your medications
  • How should NOURIANZ be taken?
      • Take NOURIANZ exactly as your healthcare provider tells you to.
      • Take NOURIANZ one time each day
      • You can take NOURIANZ with or without food
      • If you take too much NOURIANZ, call your healthcare provider or go to the nearest hospital emergency room right away
  • What are the ingredients in NOURIANZ?
    • The active ingredient in NOURIANZ is istradefylline. The inactive ingredients are crospovidone, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyvinyl alcohol, hypromellose, polyethylene glycol 3350, titanium dioxide, triacetin, iron oxide red, iron oxide yellow, and carnauba wax.

  • Is there financial support for out-of-pocket treatment costs for NOURIANZ?
    • If your doctor has prescribed NOURIANZ and you need help with the out-of-pocket cost, the Kyowa Kirin Cares program may be able to help.

      Eligible commercially insured patients may pay as little as $20 for a 1-month supply of NOURIANZ. For full program eligibility requirements, terms, conditions, and limitations, click here.

      Kyowa Kirin Cares also provides information, support, and other resources to eligible patients. For more information about Kyowa Kirin Cares, click here.

      If you need help paying for NOURIANZ, the Kyowa Kirin Cares program may be able to help you get the information and resources you need to start and stay with NOURIANZ.

      Visit Kyowa Kirin Cares for more information, including full eligibility requirements, terms, and conditions.

Organizations for patients with Parkinson's disease (PD) and their care partners

  • The Michael J. Fox Foundation is dedicated to finding a cure for PD through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson’s today.

    Learn more
  • The mission of the Parkinson’s Foundation is to make life better for people with PD through improved care and advanced research toward a cure.

    Learn more
  • The American Parkinson’s Disease Association nationwide network provides information and referrals, education and support programs, health and wellness activities, and events to facilitate a better quality of life for the PD community.

    Learn more
  • The mission of the Davis Phinney Foundation for Parkinson’s is to help people with PD live well today. The foundation provides essential information, practical tools, and inspiration to people living with PD. They fund early-phase, innovative research that focuses on exercise, speech, movement, and other factors that affect quality of life.

    Learn more
  • The mission of the Parkinson Alliance is to raise funds for research to end PD, support the development of new therapies, and improve the quality of life for those living with the disease through patient-centered research and resources.

    Learn more

This information is provided as a service by Kyowa Kirin, Inc. Inclusion in this listing is not intended to imply or suggest concurrence, endorsement, or recommendation of any organization's information or materials. No compensation or benefit has been provided to or received from Kyowa Kirin, Inc., or any of these organizations for inclusion in this list. Patients and caregivers should consult their healthcare professionals or other experts regarding the appropriate care and management of their condition.

Third-party trademarks are the property of their respective owners.

 

What is NOURIANZ?

NOURIANZ is a prescription medicine used with levodopa and carbidopa to treat adults with Parkinson’s disease (PD) who are having “off” episodes.

Before you take NOURIANZ, tell your healthcare provider about all your medical conditions, including if you:

  • have a history of abnormal movement (dyskinesia)
  • have a history of psychotic thinking or behavior
  • have reduced liver function
  • smoke cigarettes or use other tobacco products
  • are pregnant or plan to become pregnant. NOURIANZ may harm your unborn baby
  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

NOURIANZ and other medicines may affect each other causing side effects. NOURIANZ may affect the way other medicines work, and other medicines may affect how NOURIANZ works.

What are the possible side effects of NOURIANZ?
NOURIANZ may cause serious side effects, including:

  • uncontrolled sudden movements (dyskinesia). Uncontrolled sudden movements is one of the most common side effects.
  • hallucinations and other symptoms of psychosis. NOURIANZ can cause abnormal thinking and behavior, including:
    • being overly suspicious or feeling people want to harm you (paranoid ideation)
    • believing things that are not real (delusions)
    • seeing or hearing things that are not real (hallucinations)
    • confusion
    • increased activity or talking (mania)
    • disorientation
    • aggressive behavior
    • agitation
    • delirium (decreased awareness of things around you)
  • unusual urges (impulse control or compulsive behaviors). Some people taking NOURIANZ get urges to behave in a way unusual for them. Examples of this are unusual urges to gamble, increased sexual urges, strong urges to spend money, binge eating, and the inability to control these urges.

If you notice or your family notices that you are developing any new or unusual symptoms or behaviors, talk to your healthcare provider.

The most common side effects of NOURIANZ include uncontrolled movements (dyskinesia), dizziness, constipation, nausea, hallucinations, and problems sleeping (insomnia).

These are not all the possible side effects of NOURIANZ.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Patient Information for NOURIANZ.

Reference: 1. NOURIANZ [package insert]. Kyowa Kirin, Inc., Bedminster, NJ, USA.

References: 1. Hickey P, Stacy M. Available and emerging treatments for Parkinson’s disease: a review. Drug Des Devel Ther. 2011;5:241-254. 2. The voice of the patient: Parkinson’s disease. Silver Spring, MD: US Food and Drug Administration; April 2016. https://www.fda.gov/media/124392/download. Accessed June 11, 2019. 3. Parkinson’s Foundation. Statistics. https://parkinson.org/Understanding-Parkinsons/Statistics. Accessed May 5, 2019. 4. Stocchi F, Antonini A, Barone P, et al. Early DEtection of wEaring off in Parkinson disease: the DEEP study. Parkinsonism Relat Disord. 2014;20(2):204-211. 5. NOURIANZ [package insert]. Kyowa Kirin, Inc., Bedminster, NJ, USA.

References: 1. Data on file. 2. NOURIANZ [package insert]. Kyowa Kirin, Inc., Bedminster, NJ, USA.

Reference: 1. NOURIANZ [package insert]. Kyowa Kirin, Inc., Bedminster, NJ, USA.