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NOURIANZ® can fit into your schedule with a once-daily pill.

NOURIANZ can be taken any
time, with or without food.

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NOURIANZ once-daily dosing can be flexible

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  • NOURIANZ® (istradefylline)
    comes in 20 mg and 40 mg
    strengths    —you and your doctor
    will work together to figure out
    which dosage works for you
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  • Take NOURIANZ exactly as your
    doctor tells you to
  • If you take too much NOURIANZ, call
    your doctor or go to the nearest
    hospital emergency room right away
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  • NOURIANZ should be stored at room
    temperature between 68°F to 77°F
    (20°C to 25°C)
  • Keep NOURIANZ and all medicines
    out of the reach of children

Before you take NOURIANZ, tell your healthcare provider about all your medical conditions, including if you:

  • have a history of abnormal movement (dyskinesia)
  • have reduced liver function
  • smoke cigarettes
  • are pregnant or plan to become pregnant. NOURIANZ may harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if NOURIANZ passes into breast milk. You and your healthcare provider should decide if you will take NOURIANZ or breastfeed
Icon showing a list for your doctor

If your Parkinson’s symptoms are starting to return, ask your doctor about adding a treatment that works differently.

NOURIANZ HAS BEEN PRESCRIBED TO
MORE THAN 100,000 PEOPLE LIVING WITH
PARKINSON’S IN THE US AND JAPAN.

Image symbolizing number of people that have been prescribed NOURIANZ® (istradefylline)
An icon of prescription pad
If “off” time is keeping you
from moments that matter to you,
ask your doctor about adding
once-daily NOURIANZ.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

NOURIANZ and other medicines may affect each other causing side effects. NOURIANZ may affect the way other medicines work, and other medicines may affect how NOURIANZ works.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

An icon of prescription pad

If “off” time is keeping you
from moments that matter to
you, ask your doctor about
adding once-daily NOURIANZ.

How
NOURIANZ
Works Getting
NOURIANZ
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What is NOURIANZ?

NOURIANZ is a prescription medicine used with levodopa and carbidopa to treat adults with Parkinson’s disease (PD) who are having “off” episodes. It is not known if NOURIANZ is safe and effective in children.

Important Safety Information

Before you take NOURIANZ, tell your healthcare provider about all your medical conditions, including if you:

  • have a history of abnormal movement (dyskinesia)
  • have reduced liver function
  • smoke cigarettes
  • are pregnant or plan to become pregnant. NOURIANZ may harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if NOURIANZ passes into breast milk. You and your healthcare provider should decide if you will take NOURIANZ or breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

NOURIANZ and other medicines may affect each other causing side effects. NOURIANZ may affect the way other medicines work, and other medicines may affect how NOURIANZ works.

What are the possible side effects of NOURIANZ?
NOURIANZ may cause serious side effects, including:

  • uncontrolled sudden movements (dyskinesia). Uncontrolled sudden movements is one of the most common side effects.
  • hallucinations and other symptoms of psychosis. NOURIANZ can cause abnormal thinking and behavior, including:
    • being overly suspicious or feeling people want to harm you (paranoid ideation)
    • believing things that are not real (delusions)
    • seeing or hearing things that are not real (hallucinations)
    • confusion
    • increased activity or talking (mania)
    • disorientation
    • aggressive behavior
    • agitation
    • delirium (decreased awareness of things around you)
  • unusual urges (impulse control or compulsive behaviors). Some people taking NOURIANZ get urges to behave in a way unusual for them. Examples of this are unusual urges to gamble, increased sexual urges, strong urges to spend money, binge eating, and the inability to control these urges.

If you notice or your family notices that you are developing any new or unusual symptoms or behaviors, talk to your healthcare provider.

The most common side effects of NOURIANZ include uncontrolled movements (dyskinesia), dizziness, constipation, nausea, hallucinations, and problems sleeping (insomnia).

These are not all the possible side effects of NOURIANZ.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see Patient Information for NOURIANZ.